Techniques in Molecular Biology - Biology / Chemistry 330

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ANNOUNCEMENTS / HANDOUTS

Bioinformatics - Week 3 - SARS-CoV-2 lab 1

All necessary links for the lab are found within the PDF in the Block 1 folder in Blackboard (section 02 site), but are repeated below for your convenience.

Links

Part I - Searching for Genes in the 2019 Novel Coronavirus (nCoV2019, now SARS-CoV-2) Genome

fgenesV - virus-specific genefinder at Softberry.

NCBI BLAST Server

Part II - Animal origins of human coronaviruses, including SARS-CoV-2

NCBI Virus genomes database

References

Cui et al., 2019. Origin and evolution of pathogenic coronaviruses. Nature Reviews Microbiology 17: 181-192. https://www.nature.com/articles/s41579-018-0118-9

Han, 2020. Pangolins harbor SARS-CoV-2-related coronaviruses. Trends in Microbiology 28: 515–517. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136945/

Li et al., 2005. Bats Are natural reservoirs of SARS-like coronaviruses. Science 310: 676-679. https://science.sciencemag.org/content/310/5748/676

Zhou et al., 2020. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature 579: 270–273. https://www.nature.com/articles/s41586-020-2012-7