Developmental Biology Links

Biology 376 - Developmental Biology Links

30 August 19

(Note: these are mostly external links; for local class resources go to the announcements/handouts page)

Reading (Lab 1) on microscopy and how cells are studied from 'Molecular Biology of the Cell,' 4th Edition, Alberts et al., 2002.

Chapter 9 intro - Visualizing Cells

Looking at the Structure of Cells in the Microscope - read through the section entitled 'The Confocal Microscope Produces...'

Supplemental reading on Nomarski/DIC microscopy

What is C. elegans? (short reading)

Introduction to C. elegans from C. elegans II at the NCBI bookshelf

Introduction to C. elegans - YouTube lecture (26 min)

For C. elegans neuronal patterning / RNAi projects:

Introduction to C. elegans from C. elegans II at the NCBI bookshelf
Notes on lin-39 and RNAi-related papers
Table of Wnt pathway genes in C.elegans, including our available clones
The Wnt Homepage by Roel Nusse
Wormbook - see especially the sections on signal transduction, including
- Wnt signaling, Eisenmann 2005 version
- Wnt signaling, Sawa & Korswagen 2013 version
- RTK/Ras/MAPK signaling, and
- Roles of chromatin factors in C. elegans development
  Note that chromatin structure regulators in the Polycomb and trithorax classes (SET domain proteins) are known regulators of Hox genes, like lin-39.

Some Ethanol Teratogenesis related links

Comparison of Proportions - statistical test for percentages (need percentage and 'n'); uses a Chi-squared test.

Links retained from previous years:

Good General Developmental Biology Links

Gilbert's Developmental Biology - Home page for our textbook

The Virtual Embryo - another textbook/class-based site

Developmental Biology Online - includes basic embryology, such as whole mounts and serial cross sections of frog and chick embryos

Embryology - A Tulane Univ class website with all the Chick embryo serial cross sections

2006 Nobel Prize for RNA Interference Discovery in C. elegans

2002 Nobel Prize for C. elegans Developmental Biology

Society for Developmental Biology - Contains information on research done by Society members, a Virtual Library dedicated to developmental biology, forums to discuss relevant topics and news on society events.

Online access to the journal Developmental Biology

BMC Developmental Biology - an open-access online journal - all articles freely available online.

Teratology Society Home Page - A website with additional information on current research of abnormal development and birth defects. This site has a special emphasis in prevention and is geared towards professionals, students and the general public.

Signaling pathway-related links

The Hedgehog signaling pathway database - from the Ramirez-Weber Lab at San Francisco State University

The Wnt homepage - by Roel Nusse at Stanford University

Stem Cells and Cloning

Conceiving a Clone - This site provides a timeline, list of techniques, and debates on cloning as well as allows you to virtually create a clone.

Genetic Mosaics - This site explains how mice can be made mosaic. It also goes into how mosaicism can occur in humans.

The Roslin Institute - famous for cloning the sheep "Dolly."

Stem Cell Basics - NIH site with information on stem cells. The site also includes a description of stem cell applications, current research, and a summary of basics.

Embryonic stem cell research: an ethical dilemma - from EuroStemCell

Ethical issues in stem cell research - a reveiw article

The Stem Cell Debate: Is it Over? - from Learn.Genetics

Drosophila links

The 1995 Nobel Prize for studies in Drosophila developmental biology

FlyNome - stories explaining the origin of some Drosophila gene names, many odd, informative or amusing.

Homophila (rhymes with Drosophila) - a serious database (although you couldn't tell by the home page graphics) matching Human disease genes to Drosophila homologs.

Developmental Neurobiology links

Growth Cones - from the Letourneau lab at Univ of Minnesota

DrLetour's YouTube channel - cool good growth cone videos